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KMID : 0380620190510020182
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Korean Journal of Food Science and Technology
2019 Volume.51 No. 2 p.182 ~ p.187
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Superhongmi bran extract improves lipid profile and menopause symptoms: a randomized, placebo-controlled clinical trial
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Chung Soo-Im
Nan Su-Jin
Liang Jie
Ma Jing Wen
Kang Mi-Young
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Abstract
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Women who undergo natural menopause transition have increased numbers of risk factors relating to metabolic syndrome due to estrogen deficiency. This study was conducted to investigate the effect of Superhongmi bran extract on metabolic syndrome improvement in menopausal women. Thirty women, who participated in a randomized, double-blind, placebo-controlled trial, were assigned to placebo-control (n=15) or Superhongmi bran extract (n=15) groups and were asked to consume two tablets (350 mg per extract per tablet) per day. After 12 weeks, weight, body mass index (BMI), plasma triglyceride (TG) levels, and total cholesterol (TC) levels were significantly decreased, whereas HDL-cholesterol (HDL-C), apolipoprotein A1 (ApoA1), adiponectin, superoxide dismutase 1 (SOD1), and GSH (glutathione) concentrations were significantly increased in the Superhongmi bran extract group. Moreover, 17β-estradiol, and progesterone levels in the Superhongmi group were significantly higher than those in the placebo-control group. These results suggest that Superhongmi bran extract alleviates metabolic symptom in menopausal women.
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KEYWORD
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functional rice, Superhongmi, metabolic symptoms, menopause, hormone replacement therapy
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